Catalytic Hydration of Nitriles to h i d e s PLATINUM - CONTAINING CATALYST OFFERS NEW OPPORTUNITY
نویسنده
چکیده
The hydration of nitriles to amides is one of the basic transformations in organic chemistry However, it is not generally appreciated how diflicult this transformation is to carry out efficient13 since amides themselves undergo further hydrolysis to the acid. While nicotinamide and acrylamide are usually manufactured from the corresponding nitriles using metallic copper heterogeneous catalysts, applications in the fine chemicals industry are rare. Now, the use of a new platinum-containing homogeneous catalyst applicable to complex organic nitriles containing sensitive functional groups will create an opportunity for nitrile hydration in thefine chemical and pharmaceutical industries.
منابع مشابه
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